Relay Therapeutics to Present Updated Clinical Data on RLY-2608 in HR+/HER2- Breast Cancer at 2024 San Antonio Breast Cancer Symposium

Democrats proved they’re not defenders of democracyTracing fentanyl’s path into the US starts at this port. It doesn’t end there.

Greyhound racing will be phased out in New Zealand over the next 20 months, says Winston Peters . Urgent laws will prevent the unnecessary killing of racing dogs during the transition. Multiple reviews and high injury rates prompted the decision, with cross-party support for the ban. The SPCA has called the decision a ‘great day’ for greyhounds. Greyhound racing is set to be outlawed in New Zealand in a decision announced by Racing Minister Winston Peters. A proposal to ban the sport follows three critical reviews of the industry and a persistently high number of dogs being injured in races that Peters says is “unacceptable”. “This is not a decision that is taken lightly but is ultimately driven by protecting the welfare of racing dogs,” he said. The sport won’t stop immediately but will be phased out gradually over the next 20 months to allow time to rehome the estimated 2900 racing dogs in the industry. This would mean the last official greyhound racing event in New Zealand would be in July 2026 if not sooner. STORY CONTINUES AFTER LIVEBLOG STORY CONTINUES Urgent laws are also being passed to prevent racing dogs being killed amid moves to end the sport. Concerns about poor animal welfare standards have been an issue for years. There have been allegations a top trainer used live animals to train his dogs , multiple racing dogs have tested positive for methamphetamine and dozens of dogs have been put down after suffering catastrophic injuries while racing. In the most recent 2023-24 season, Greyhound Racing New Zealand’s (GRNZ) animal welfare report said nine dogs were euthanised because of injuries suffered during a race, up from seven the season before; 224 dogs suffered serious injuries and a further 672 had injuries classified as “minor and medium” in the past season, according to the report. Though GRNZ has made progress on reducing the death rate, it was the inability to significantly cut the number of race-day injuries that was the catalyst for Peters to bring the axe down. “The time has come to do the right thing,” he said. The move to ban greyhound racing will be subject to a select committee process where public submissions on the plan will be considered. Urgent law to prevent unnecessary killing New laws will be passed today to try to prevent the unnecessary killing of racing dogs after publicity over plans to ban the sport. The Racing Industry (Unlawful Destruction of Specified Greyhounds) Amendment Bill will be passed under urgency this afternoon. “Keeping unwanted dogs safe is a priority. The Government is working with animal welfare organisations such as the SPCA to establish programmes to support rehoming,” Peters said. A ministerial advisory committee has been set up to provide advice on the transition away from the sport over the next 20 months, and it will be chaired by Heather Simpson. Peters said there was cross-party support from Labour and the Greens to end greyhound racing. While there will be the opportunity to oppose the plan during the select committee submissions process, Peters said the Government’s position was to “in principle, end greyhound racing”. A history of critical reviews The previous Labour Government put the industry on notice after a series of alarming reports highlighting a high rate of injuries and deaths, and questions about the transparency of those who oversee the sport. In 2017, Rodney Hansen QC’s review revealed more than 1440 dogs had been euthanised in only four years , some dogs were “unaccounted” for, there was poor record-keeping and low numbers of greyhounds had been rehomed. Peters, who was Racing Minister in 2017, said at the time Hansen’s findings were “disturbing”. In 2021, then- Racing Minister Grant Robertson put the industry on notice after another critical review. Robertson accused GRNZ of “unnecessarily obfuscating information” and being reluctant to share pertinent data. Then, last year, the industry was again warned it was on thin ice after a report from the Racing Integrity Board was published . Briefing papers to Peters obtained under the Official Information Act show officials said Cabinet must decide whether the sport had the social licence to continue in New Zealand and will probably be a “value-based/political decision”. New Zealand is among only five countries where greyhound racing is still legal and practised. Australia, the United Kingdom and Ireland still allow greyhound racing. The United States has only two operational racing tracks. In Mexico and Vietnam where it’s still legal, there are no functional tracks for dog racing. Over many years, there has been a sustained campaign to end greyhound racing by animal rights groups including Save Animals From Exploitation (Safe), the SPCA and Helping You Help Animals (Huha). Last week, a survey by the SPCA found three-quarters of New Zealanders would vote to ban commercial greyhound racing if the decision were put to a public referendum. ‘A great day for greyhounds’ SPCA chief scientific officer Arnja Dale told the Herald she was delighted the Racing Minister had reached the decision to end greyhound racing. “We applaud Minister Peters for making this amazing decision. It is a great day for greyhounds. It is a win for greyhounds.” The SPCA has set up a rehoming coalition with several other partners and Dale is confident they have the ability to ensure all ex-racing dogs get placed into “loving, family homes”. “The sport is inherently dangerous. The injury and death rates make it unsustainable, and we are absolutely delighted to be worthing with the Deputy Prime Minister and Department of Internal Affairs to rehome all these dogs,” she said. Dale said the SPCA would do all it could to support the industry get the best outcome for the dogs and it expected a “slow and steady” supply of former racing dogs to be placed with the organisation and its foster network. “The SPCA is always busy at this time of year, but we have been planning for this eventuality and have strategies in place to move animals around, so we have more room for greyhounds.” Michael Morrah is a senior investigative reporter/team leader at the Herald . He won the best coverage of a major news event at the 2024 Voyager NZ Media Awards and has twice been named reporter of the year. He has been a broadcast journalist for 20 years and joined the Herald ’s video team in July 2024. Share this article Copy Link Email Facebook Twitter/X LinkedIn Reddit

Giants release quarterback Daniel Jones just days after benching him EAST RUTHERFORD, N.J. (AP) — The Daniel Jones era in New York is over. The Giants quarterback was granted his release by the team just days after the franchise said it was benching him in favor of third-stringer Tommy DeVito. New York president John Mara said Jones approached the team about releasing him and the club obliged. Mara added he was “disappointed” at the quick dissolution of a once-promising relationship between Jones and the team. Giants coach Brian Daboll benched Jones in favor of DeVito following a loss to the Panthers in Germany that dropped New York's record to 2-8. Conor McGregor must pay $250K to woman who says he raped her, civil jury rules LONDON (AP) — A civil jury in Ireland has awarded more than $250,000 to a woman who says she was raped by mixed martial arts fighter Conor McGregor in a Dublin hotel penthouse after a night of heavy partying. The jury on Friday awarded Nikita Hand in her lawsuit that claimed McGregor “brutally raped and battered” her in 2018. The lawsuit says the assault left her heavily bruised and suffering from post-traumatic stress disorder. McGregor testified that he never forced her to do anything and that Hand fabricated her allegations after the two had consensual sex. McGregor says he will appeal the verdict. Week 16 game between Denver Broncos and Los Angeles Chargers flexed to Thursday night spot The Los Angeles Chargers have played their way into another prime time appearance. Justin Herbert and company have had their Dec. 22 game against the Denver Broncos flexed to Thursday night, Dec. 19. Friday’s announcement makes this the first time a game has been flexed to the Thursday night spot. The league amended its policy last season where Thursday night games in Weeks 13 through 17 could be flexed with at least 28 days notice prior to the game. The matchup of AFC West division rivals bumps the game between the Cleveland Browns and Cincinnati Bengals to Sunday afternoon. NBA memo to players urges increased vigilance regarding home security following break-ins MIAMI (AP) — The NBA is urging its players to take additional precautions to secure their homes following reports of recent high-profile burglaries of dwellings owned by Milwaukee Bucks forward Bobby Portis and Kansas City Chiefs teammates Patrick Mahomes and Travis Kelce. In a memo sent to team officials, a copy of which was obtained by The Associated Press, the NBA revealed that the FBI has connected some burglaries to “transnational South American Theft Groups” that are “reportedly well-organized, sophisticated rings that incorporate advanced techniques and technologies, including pre-surveillance, drones, and signal jamming devices.” Red Bull brings wrong rear wing to Las Vegas in mistake that could stall Verstappen's title chances LAS VEGAS (AP) — Max Verstappen is suddenly in jeopardy of being denied a fourth consecutive Formula 1 title Saturday night. Red Bull apparently brought the wrong rear wing to Las Vegas and GPS data showed its two cars to be significantly slower on the straights than both McLaren and Mercedes, which led both practice sessions. Red Bull says it doesn’t have a replacement rear wing in Las Vegas to fix the issue and little chance of getting two flown in from England ahead of the race. Caitlin Clark to join Cincinnati bid for 16th National Women's Soccer League team WNBA star Caitlin Clark has joined Cincinnati’s bid for an expansion National Women’s Soccer League team. Major League Soccer franchise FC Cincinnati is heading the group vying to bring a women’s pro team to the city. The club issued a statement confirming Clark had joined the bid group. NWSL Commissioner Jessica Berman has said the league plans to announce the league’s 16th team by the end of the year. The league's 15th team will begin play in 2026 in Boston. Aaron Judge won't be bothered if Juan Soto gets bigger contract from Yankees than his $360M deal NEW YORK (AP) — Aaron Judge won’t be bothered if Juan Soto gets a bigger deal from the New York Yankees than the captain’s $360 million, nine-year contract. Speaking a day after he was a unanimous winner of his second MVP, Judge says “It ain’t my money” and adds "that’s never been something on my mind about who gets paid the most.” Judge led the major leagues with 58 homers, 144 RBIs and 133 walks while hitting .322. Soto batted .288 with 41 homers, 109 RBIs and 129 walks in his first season with the Yankees, then became a free agent at age 26. In a 'Final Four-type weekend,' two top-6 clashes put women's college basketball focus on West Coast LOS ANGELES (AP) — Two games featuring four powerhouse teams has put the focus in women's college basketball on the West Coast this weekend. JuJu Watkins and No. 3 Southern California host Hannah Hidalgo and No. 6 Notre Dame on Saturday. Top-ranked South Carolina visits Lauren Betts and fifth-ranked UCLA on Sunday. Both games are nationally televised and the arenas are expected to be packed. WNBA scouts will be on hand to check out some of the nation's top talent. Two teams will come away with their first losses of the season. USC coach Lindsay Gottlieb calls it “a Final Four-type weekend.” A documentary featuring Watkins will air on NBC ahead of USC's game, which leads into the Army-Notre Dame football game. Noodles and wine are the secret ingredients for a strange new twist in China's doping saga Blame it on the noodles. That's what one Chinese official suggested when anti-doping leaders were looking for answers for the doping scandal that cast a shadow over this year's Olympic swim meet. Earlier this year, reports that 23 Chinese swimmers had tested positive for a banned heart medication emerged. None were sanctioned because Chinese authorities determined the swimmers were contaminated by traces of the drug spread about a hotel kitchen. In a strange twist, the leader of China's anti-doping agency suggested this case could have been similar to one in which criminals were responsible for tainting noodles that were later eaten by another Chinese athlete who also tested positive for the drug. Athletes see climate change as threatening their sports and their health. Some are speaking up BAKU, Azerbaijan (AP) — Pragnya Mohan has been a professional triathlete for nearly a decade, but summers in her native India are now so hot that she can’t train there anymore. And she worries about a day when heat around the world kills her sport entirely. She was among athletes who spoke at the United Nations climate summit in Azerbaijan about the threat global warming poses to them, to fans and to sport itself. They described how extreme weather is making training and competing difficult or impossible. With billions of fans worldwide, some athletes and leagues are trying to get more people to care, and act, on climate change.Weatherford Stock Hits 52-Week Low at $76.91 Amid Market Challenges

President Joe Biden ’s administration is set to initiate a trade investigation into Chinese semiconductors in the coming days, as part of a push to reduce reliance on a technology that US officials believe pose national security risks. The probe could result in tariffs or other measures to restrict imports on older-model semiconductors and the products containing them, including medical devices, cars, smartphones and weaponry, according to people familiar with the matter. The investigation examining so-called foundational chips could take months to conclude, meaning that any reaction to the findings will be left to the discretion of President-elect Donald Trump ’s incoming team. Biden officials have for months debated whether to initiate the investigation under Section 301, which allows the US to impose restrictions on countries with unfair trade practices, the people said. This week, White House officials agreed to move forward with the inquiry that could help protect the US chip industry. Approving the probe now means that the new Trump administration will likely have the option to impose trade restrictions to protect domestic semiconductor production in the early months of the president-elect’s term. Bolstering the US semiconductor industry has been a key focus for Biden, who has taken aggressive steps to limit advanced US technology from being exported to China. Biden signed into law legislation that provided billions of dollars of incentives for chipmakers to build semiconductor factories in the US to stave off a need for cheaper Chinese-made chips. Spokespeople for the National Security Council and the US Trade Representative declined to comment. Global Competition The White House has used the past two years to implement export restrictions on advanced semiconductors made with American and allied technology. But in the meantime, China has been able to manufacture the older, widely available types of semiconductors at a lower cost than their competitors. Biden officials worry that without restrictions, Beijing will flood the US and global markets with inexpensive chips that will undercut other companies and run them out of business. In May, the White House announced it will increase tariffs on Chinese legacy semiconductors from the current 25% rate to 50% by 2025. But the Biden team largely agreed that was not enough to prevent a market disruption in the future, especially as the US is looking to increase domestic production of semiconductors. To impose those tariffs, Biden used the same authority Trump employed to levy more than $300 billion in tariffs on Chinese goods during his first term.

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Presentations include analytical validation of Myriad's high-definition tumor informed MRD assay for breast cancer and its Breast Cancer Risk Assessment Tool MyRisk® with RiskScore® SALT LAKE CITY, Dec. 09, 2024 (GLOBE NEWSWIRE) -- Myriad Genetics, Inc . (NASDAQ: MYGN), a leader in genetic testing and precision medicine, announced it will present new data at the 2024 San Antonio Breast Cancer Symposium ® (SABCS), including a spotlight presentation on a breast cancer risk assessment tool that combines a polygenic score for all ancestries. Additional new data will show how Myriad's second-generation tumor-informed molecular residual disease (MRD) assay demonstrated high sensitivity, specificity and measurement accuracy, which, together, will facilitate improved resolution in residual-disease detection and extend lead times in recurrence detection. "We are very excited to share validation data of our MRD assay. SABCS gives us the opportunity to showcase our clinical expertise in the prevention and treatment of early and advanced breast cancer,” said George Daneker, MD, President and Chief Clinical Officer, Oncology, Myriad Genetics. "Myriad is one of the only labs that can offer germline and tumor genomic testing, combined with customizable workflow solutions and point-of-care patient education sessions. Our test results are supported by treatment-focused reporting, concordance checks between germline and tumor genomic results, and a summary sheet designed to help oncologists and breast surgeons interpret actionable insights more effectively.” Myriad Genetics Data Presentations Spotlight Presentation: Session 16, PS16-01: Polygenic Risk Date: Thursday, Dec. 12, 2024, 5:30-7:00 pm (CST), Hemisfair Ballroom 3 Presenter: Timothy Simmons, PhD, Biostatistician III, Myriad Genetics The presentation will share longitudinal validation in the UK Biobank of a breast cancer risk assessment tool that combines a polygenic score for all ancestries with traditional risk factors. Rapid-Fire Presentation: RF1-06 Date: Wednesday, Dec. 11, 2024, 12:00-12:50 pm (CST), Hall 1 Presenter: Katie Johansen Taber, PhD, Vice President, Clinical Product Research & Partnerships, Myriad Genetics Dr. Johansen Taber will share data detailing the association of polygenic-based breast cancer risk prediction with patient management. Poster Presentation: P2-04-23 Date: Wednesday, Dec. 11, 2024, 5:30-7:00 pm (CST), Halls 2-3 Presenter: Ashley Acevedo, PhD, Staff Computational Scientist, Myriad Genetics This poster shares the analytical validation of a high-definition tumor-informed Molecular Residual Disease (MRD) assay to demonstrate robust detection at low-tumor fractions, which are common in breast cancer. Poster Presentation: P3-02-10 Date: Thursday, Dec. 12, 2024, 12:30-2:00 pm (CST), Halls 2-3 Presenter: Holly Pederson, MD, Cleveland Clinic Dr. Pederson will share her evaluation of a polygenic risk score as a predictor of breast cancer, triple-negative breast cancer, and early-onset disease in Hispanic women. In addition to data presentations, Myriad will welcome attendees to its booth (#1327) during exhibition hours. Among the Myriad products highlighted in the company's SABCS exhibit are: Myriad Genetics is a leading genetic testing and precision medicine company dedicated to advancing health and well-being for all. Myriad develops and offers genetic tests that help assess the risk of developing disease or disease progression and guide treatment decisions across medical specialties where genetic insights can significantly improve patient care and lower healthcare costs. For more information, visit www.myriad.com . Safe Harbor Statement This press release contains "forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, including that the company will present new data at SABCS and that the company's new data that will be shared at SABCS will show how the company's second-generation tumor-informed MRD assay demonstrated high sensitivity, specificity and measurement accuracy, which, together, will facilitate improved resolution in residual-disease detection and extend lead times in recurrence detection. These "forward-looking statements” are management's expectations of future events as of the date hereof and are subject to known and unknown risks and uncertainties that could cause actual results, conditions, and events to differ materially and adversely from those anticipated. Such factors include those risks described in the company's filings with the U.S. Securities and Exchange Commission, including the company's Annual Report on Form 10-K filed on February 28, 2024, as well as any updates to those risk factors filed from time to time in the company's Quarterly Reports on Form 10-Q or Current Reports on Form 8-K. Myriad is not under any obligation, and it expressly disclaims any obligation, to update or alter any forward-looking statements, whether as a result of new information, future events or otherwise except as required by law. Investor Contact Matt Scalo (801) 584-3532 [email protected] Media Contact Glenn Farrell (385) 318-3718 [email protected]

BOSTON, Dec. 09, 2024 (GLOBE NEWSWIRE) -- Block & Leviton announces that a securities fraud lawsuit has been filed against Kyverna Therapeutics, Inc. KYTX and certain of its executives. Investors who have lost money in their Kyverna Therapeutics, Inc. investment should contact the firm to learn more about how they might recover those losses. For more details, visit https://blockleviton.com/cases/kytx . What is this all about? Kyverna Therapeutics has been sued for securities law violations. The lawsuit alleges that at the time of the company's February 2024 IPO, it knew adverse data about one of Kyverna's drug trials, which it kept from the market, in violation of federal securities laws. Those who purchased Kyverna shares traceable to the company's IPO may be eligible to recover for their losses. Who is eligible? Anyone who purchased Kyverna Therapeutics, Inc. common stock between February 07, 2024 and December 09, 2024 and has seen their shares fall may be eligible, whether or not they have sold their investment. Investors should contact Block & Leviton to learn more. What should you do next? The deadline to seek appointment as lead plaintiff is February 07, 2025. A class has not yet been certified, and until a certification occurs, you are not represented by an attorney. If you choose to take no action, you can remain an absent class member. If you've lost money on your investment, you should contact Block & Leviton to learn more via our case website , by email at shareholders@blockleviton.com , or by phone at (888) 256-2510. Whistleblower? If you have non-public information about Kyverna Therapeutics, Inc., you should consider assisting in our investigation or working with our attorneys to file a report with the Securities Exchange Commission under their whistleblower program. Whistleblowers who provide original information to the SEC may receive rewards of up to 30% of any successful recovery. For more information, contact Block & Leviton at whistleblowers@blockleviton.com or by phone at (888) 256-2510. Why should you contact Block & Leviton? Block & Leviton is widely regarded as one of the leading securities class action firms in the country. Our attorneys have recovered billions of dollars for defrauded investors and are dedicated to obtaining significant recoveries on behalf of our clients through active litigation in the federal courts across the country. Many of the nation's top institutional investors hire us to represent their interests. You can learn more about us at our website, www.blockleviton.com , call (888) 256-2510 or email shareholders@blockleviton.com with any questions. This notice may constitute attorney advertising. CONTACT: BLOCK & LEVITON LLP 260 Franklin St., Suite 1860 Boston, MA 02110 Phone: (888) 256-2510 Email: shareholders@blockleviton.com © 2024 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.Games on a college basketball schedule don't contrast much more than the two NC State has this week. The Wolfpack (6-3) host Coppin State (0-10) on Tuesday in Raleigh, N.C., then hit the road to challenge No. 10 Kansas on Saturday. NC State enters its unusual week after snapping a three-game skid with an 84-74 overtime win at home Saturday against Florida State in its Atlantic Coast Conference opener. Transfers Marcus Hill and Dontrez Styles each had their season high, scoring 23 and 21 points, respectively. They scored 13 of NC State's 14 points in overtime. "Dontrez Styles was tremendous," Wolfpack coach Kevin Keatts said. "In the second half, he made play after play." Hill, who was the top scorer last year at Bowling Green (20.5 points per game), and Styles, who was the second-leading scorer last year at Georgetown (12.8 ppg), combined to hit 14 of 25 shots and pull down 11 rebounds. The win followed defeats to then-No. 13 Purdue and BYU, both by double-digit margins, in the Rady Children's Invitational and a 63-59 loss to Texas in the SEC/ACC Challenge. "The little things that impact the game are defending, making free throws and blocking out," Keatts said. "We handled that much better than we did against Texas." Coppin State arrives in Raleigh on a 23-game losing streak dating to January -- the longest current run of futility in Division I. Each of the Eagles' losses this season have come by double-digit margins, though they have been more competitive lately, falling to Baltimore rival Loyola (Md.) 68-57 and at Wagner 65-52 last week. Julius Ellerbe III has been one of Coppin's most reliable players lately, scoring a combined 20 points in the last two games. He had 16 points and 12 rebounds in a loss to George Mason last month. Teammate Peter Oduro recorded a double-double, with 16 points and 10 rebounds, in last month's loss at Saint Joseph's. "These things take time," Coppin State second-year coach Larry Stewart said. "It takes time to establish your culture. It takes time to get the right players in your system." --Field Level Media

Vice President Kamala Harris rarely, if ever, brought up transgender rights during her 2024 presidential bid — but President-elect Donald Trump did, devoting . Yahoo News reporter Andrew Romano breaks down a new Yahoo News/YouGov poll that shows how that $37 million investment appears to have paid off at the ballot box.

Three-game skid over, NC State faces winless Coppin State

NoneThe newly created position underscores the president-elect’s intent to boost two rapidly developing industries.